Arne Holmgren Selected Research

Glutaredoxins

1/2022	Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice.
1/2017	Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia.
12/2015	Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patients.
4/2014	Plasma glutaredoxin activity in healthy subjects and patients with abnormal glucose levels or overt type 2 diabetes.
11/2008	Glutaredoxin systems.
3/2008	Expression pattern of human glutaredoxin 2 isoforms: identification and characterization of two testis/cancer cell-specific isoforms.
8/2004	Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo.

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Arne Holmgren Research Topics

Disease

33	Neoplasms (Cancer) 11/2021 - 07/2005
8	Infections 01/2019 - 01/2007
3	Inflammation (Inflammations) 01/2022 - 11/2003
3	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2016 - 08/2007
3	Cardiovascular Diseases (Cardiovascular Disease) 04/2010 - 03/2007
2	Vascular Diseases (Vascular Disease) 01/2022 - 11/2003
2	Atherosclerosis 01/2018 - 01/2007
2	Neuroblastoma 10/2017 - 08/2015
2	Neuroinflammatory Diseases 01/2017 - 02/2016
2	Type 2 Diabetes Mellitus (MODY) 12/2015 - 04/2014
2	Disease Progression 12/2015 - 01/2009
2	Virus Diseases (Viral Diseases) 01/2014 - 01/2009
2	Alzheimer Disease (Alzheimer's Disease) 10/2012 - 04/2010
2	Muscular Diseases (Myopathy) 12/2010 - 04/2010
2	Starvation 08/2009 - 05/2002
2	Hypoxia (Hypoxemia) 11/2008 - 05/2008
2	Interstitial Lung Diseases (Interstitial Lung Disease) 08/2004 - 11/2003
1	Fatty Liver 01/2022
1	Chemical and Drug Induced Liver Injury 10/2021
1	Liver Failure 10/2021
1	Staphylococcal Infections 01/2019
1	Staphylococcal Skin Infections 01/2019
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017
1	Multiple Sclerosis 01/2017
1	Demyelinating Diseases (Demyelinating Disease) 01/2017
1	Prostatic Neoplasms (Prostate Cancer) 01/2017
1	Gram-Negative Bacterial Infections 01/2017
1	Peritonitis 01/2017
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2016
1	Parasitemia 02/2016
1	Rheumatoid Arthritis 01/2016
1	Chronic Disease (Chronic Diseases) 01/2016

Drug/Important Bio-Agent (IBA)

18	ThioredoxinsIBA 01/2020 - 11/2003
10	Thioredoxin-Disulfide ReductaseIBA 01/2020 - 02/2004
10	Proteins (Proteins, Gene)FDA Link 12/2016 - 05/2002
9	EnzymesIBA 01/2022 - 11/2004
8	AntioxidantsIBA 01/2020 - 07/2005
7	GlutaredoxinsIBA 01/2022 - 08/2004
6	Pharmaceutical PreparationsIBA 07/2014 - 04/2006
5	ebselenIBA 01/2019 - 06/2002
5	Selenoproteins (Selenoprotein)IBA 11/2018 - 12/2006
5	SeleniumIBA 11/2018 - 12/2006
4	SelenocysteineIBA 01/2020 - 04/2006
4	Sulfhydryl Compounds (Thiols)IBA 11/2018 - 12/2006
4	Selenium CompoundsIBA 04/2010 - 12/2006
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 06/2016
3	MercuryIBA 10/2017 - 05/2010
3	motexafin gadoliniumIBA 08/2011 - 04/2006
3	Selenious Acid (Selenite)IBA 01/2011 - 09/2006
2	Antiviral Agents (Antivirals)IBA 11/2021 - 01/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 04/2006
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 04/2014
2	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 01/2019 - 04/2006
2	IsoenzymesIBA 11/2018 - 05/2010
2	GoldIBA 01/2018 - 01/2016
2	Glutathione (Reduced Glutathione)IBA 10/2017 - 01/2017
2	IronIBA 01/2017 - 01/2009
2	SulfurIBA 01/2017 - 01/2009
2	CurcuminIBA 01/2017 - 07/2005
2	Superoxide Dismutase-1IBA 12/2016 - 11/2004
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2016 - 01/2013
2	Cysteine (L-Cysteine)FDA Link 01/2016 - 12/2015
2	Antineoplastic Agents (Antineoplastics)IBA 12/2015 - 02/2009
2	Thyroid HormonesIBA 04/2010 - 01/2009
2	Carrier Proteins (Binding Protein)IBA 03/2007 - 01/2007
1	Glutathione Reductase (Glutathione-Disulfide Reductase)IBA 01/2022
1	GlycogenIBA 01/2022
1	LipidsIBA 01/2022
1	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2021
1	Carboplatin (JM8)FDA LinkGeneric 01/2020
1	Indicators and Reagents (Reagents)IBA 01/2020
1	Cisplatin (Platino)FDA LinkGeneric 01/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2019
1	Dehydroascorbic AcidIBA 01/2019
1	Vitamin K 3 (Menadione)FDA Link 01/2019
1	DeoxyribonucleotidesIBA 01/2019
1	Lipid PeroxidesIBA 11/2018
1	methylselenic acidIBA 11/2018
1	methaneselenolIBA 11/2018
1	Protein Kinase CIBA 11/2018
1	PlatinumIBA 01/2018
1	eprenetapoptIBA 01/2018
1	Insulin (Novolin)FDA Link 01/2018
1	MetalsIBA 01/2018
1	AndrogensIBA 01/2017
1	3-nitrotyrosineIBA 01/2017
1	SilverIBA 01/2017
1	Silybin (Lagosa)IBA 01/2017
1	ResveratrolIBA 01/2017
1	MelatoninIBA 01/2017
1	Caspase 3 (Caspase-3)IBA 01/2016
1	JNK Mitogen-Activated Protein KinasesIBA 01/2016
1	PhytochemicalsIBA 01/2016
1	Auranofin (Ridaura)FDA Link 01/2016
1	Thioredoxin Reductase 1IBA 12/2015

Therapy/Procedure

8	Therapeutics 01/2020 - 09/2006
3	Chemoprevention 01/2010 - 04/2006
1	Investigational Therapies (Experimental Therapy) 01/2019